Home Transmembrane Transporters Calcium Channel antagonist - AChR antagonist Propiverine hydrochloride For research use only.

Propiverine hydrochloride

Propiverine is an anticholinergic drug used for the treatment of overactive bladder and urinary incontinence. Propiverine is a muscarinic receptor antagonist possessing additional properties, i.e., block of L-type Ca2+ channels.

Propiverine hydrochloride Chemical Structure

Propiverine hydrochloride Chemical Structure

CAS No. 54556-98-8

Purity & Quality Control

Batch: S493101 DMSO]80 mg/mL]false]]]false]]]false Purity: 99.25%
99.25

Propiverine hydrochloride Related Products

Signaling Pathway

Calcium Channel Signaling Pathways

Calcium Channel Signaling Pathway

Biological Activity

Description Propiverine is an anticholinergic drug used for the treatment of overactive bladder and urinary incontinence. Propiverine is a muscarinic receptor antagonist possessing additional properties, i.e., block of L-type Ca2+ channels.
In Vivo
In vivo Propiverine administered orally in mice binds significantly to muscarinic receptors in the bladder and its binding activity is more prominent and longer-lasting in the bladder than in the submaxillary gland. Propiverine is well absorbed from the gastrointestinal tract and undergoes high first-pass metabolism. It is metabolized in the liver and intestine to form the active metabolites[1].
Animal Research Animal Models Mice
Dosages 74.3, 149 and 297 μmol/kg
Administration oral administration

Chemical Information & Solubility

Molecular Weight 403.94 Formula

C23H29NO3.Cl H
CAS No. 54556-98-8 SDF --
Smiles CCCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)OC3CCN(CC3)C.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 80 mg/mL ( (198.04 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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